Agar is so critical that since WWII, scientists have tried to find alternatives in the event of a supply chain breakdown, especially as recent shortages have caused similar alarm. But while other colloid jellies have emerged, agar remains integral to laboratory protocols because no alternatives can yet compete on performance, cost, and ease of use.
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The design of Web streams predates async iteration in JavaScript. The for await...of syntax didn't land until ES2018, two years after the Streams Standard was initially finalized. This timing meant the API couldn't initially leverage what would eventually become the idiomatic way to consume asynchronous sequences in JavaScript. Instead, the spec introduced its own reader/writer acquisition model — and that decision rippled through every aspect of the API.